Coding

Part:BBa_K4364001

Designed by: Slavil Peykov   Group: iGEM22_Bulgaria   (2022-10-12)


blaVIM-2 coding sequence


This part was designed and used by the iGEM Bulgaria 2022 team.


This part encodes the metallo-beta-lactamase VIM-2. This enzyme can degrade all beta-lactams except for monobactams. It was used as a core compound in the CADABRA enzyme cocktail developed by the iGEM Bulgaria 2022 team. This cell-free MBL extract is able to successfully degrade meropenem in various liquid samples thus reducing the levels of carbapenem resistance.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None